Small molecules which reverse POR Global supression
Canned Analysis
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General Information
AccessionDCA00020854
TitleSmall molecules which reverse POR Global supression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by POR Global supression in the Liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fddae467bea600fba086
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1670
Cell TypeLiver
Gene Symbol (human)POR
Gene Symbol (mouse)Por
Organismmouse
Perturbation TypeGlobal supression
None{u'vals': [-0.152162512398, 0.15212417979, -0.137341945354, 0.12126647003, -0.105326763588, -0.101771278241, -0.100711855286, -0.100489922028, 0.0983704248989, -0.0970852383632, 0.0932704105677, -0.0917122682718, 0.0904282181752, 0.0903711870031, -0.08939
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM44308, GSM44707, GSM44708
Perturbed SamplesGSM44709, GSM44710, GSM44711
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2362
Gene Expression Omnibus
NADPH-cytochrome P450 reductase-loss transgenic models: hepatic expression profiling
14
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