Small molecules which reverse POR KO
Canned Analysis
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General Information
AccessionDCA00020856
TitleSmall molecules which reverse POR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by POR KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fa2ae467bea600fb9eec
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatordsurujon
CREEDS IDgene:524
Cell Typeliver
Gene Symbol (human)POR
Gene Symbol (mouse)Por
Organismmouse
Perturbation TypeKO
None{u'vals': [0.181781915904, 0.172110858012, 0.170179525532, 0.123214587238, 0.12256745307, -0.107358331359, 0.10686727397, 0.104785981776, 0.0938038736587, 0.0908961788824, -0.0905635181917, -0.0888247007769, -0.088578434995, 0.0853526394701, 0.08478832187
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM44308, GSM44707, GSM44708
Perturbed SamplesGSM44712, GSM44713, GSM44714
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2362
Gene Expression Omnibus
NADPH-cytochrome P450 reductase-loss transgenic models: hepatic expression profiling
14
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