Small molecules which reverse NPTX1 KD
Canned Analysis
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General Information
AccessionDCA00020864
TitleSmall molecules which reverse NPTX1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NPTX1 KD in the ES cells (Neural differentiation) day 5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fdffe467bea600fba096
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1674
Cell TypeES cells (Neural differentiation) day 5
Gene Symbol (human)NPTX1
Gene Symbol (mouse)Nptx1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM850885, GSM850886, GSM850887
Perturbed SamplesGSM850900, GSM850901, GSM850902
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34551
Gene Expression Omnibus
NPTX1 is a Critical Regulator of Neural Induction in Human Pluripotent Stem Cells
28
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