Small molecules which reverse EZH2 deficiency
Canned Analysis
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General Information
AccessionDCA00020876
TitleSmall molecules which reverse EZH2 deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EZH2 deficiency in the lymph node T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b95e467bea600fbad9a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:168
Cell Typelymph node T cells
Gene Symbol (human)EZH2
Gene Symbol (mouse)Ezh2
Organismmouse
Perturbation Typedeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM26964, GSM26965, GSM26966
Perturbed SamplesGSM26967, GSM26968, GSM26969
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1566
Gene Expression Omnibus
Polycomb group protein Ezh2 deficiency effect on lymph node T cells
7
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