Small molecules which reverse IL1RN KO
Canned Analysis
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General Information
AccessionDCA00020892
TitleSmall molecules which reverse IL1RN KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IL1RN KO in the CD4+ T cells from spleen at 1 month cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23bf8e467bea600fbbbae
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1689
Cell TypeCD4+ T cells from spleen at 1 month
Gene Symbol (human)IL1RN
Gene Symbol (mouse)Il1rn
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM186552, GSM186553, GSM186554
Perturbed SamplesGSM186523, GSM186524
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7705
Gene Expression Omnibus
Microarray analysis of CD4+T cells in murine arthritis
7
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