Small molecules which reverse IL1RN KO
Canned Analysis
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General Information
AccessionDCA00020898
TitleSmall molecules which reverse IL1RN KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IL1RN KO in the spleen at 4 month cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f27ae467bea600fb9bd0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1692
Cell Typespleen at 4 month
Gene Symbol (human)IL1RN
Gene Symbol (mouse)Il1rn
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM185032, GSM185033, GSM185034
Perturbed SamplesGSM185012, GSM185013, GSM185014
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7657
Gene Expression Omnibus
Identification of phase-specific arthritis-related genes in mice
14
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