Small molecules which mimic NOTCH1 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020907
TitleSmall molecules which mimic NOTCH1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NOTCH1 KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f238e467bea600fb9bb2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1698
Cell Typeliver
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1386005, GSM1386006, GSM1386007
Perturbed SamplesGSM1386008, GSM1386009, GSM1386010
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE57655
Gene Expression Omnibus
Gene expression profiling of Notch1 knockout mouse liver samples and murine hepatic angiosarcoma cell lines.
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.