Small molecules which mimic PRMT1 KD
Canned Analysis
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General Information
AccessionDCA00020919
TitleSmall molecules which mimic PRMT1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PRMT1 KD in the ES cells (Neural differentiation) day 16 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ffa9e467bea600fba152
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1707
Cell TypeES cells (Neural differentiation) day 16
Gene Symbol (human)PRMT1
Gene Symbol (mouse)Prmt1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1147005, GSM1147006, GSM1147007
Perturbed SamplesGSM1147008, GSM1147009, GSM1147010
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47214
Gene Expression Omnibus
Expression data from D3, siSCR, siPRMT1 and siPRMT8 ES cell derived neurons
14
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