Small molecules which reverse FOXA1 OE
Canned Analysis
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General Information
AccessionDCA00020934
TitleSmall molecules which reverse FOXA1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FOXA1 OE in the Prostate cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21203e467bea600fba96a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgregmicrotask
CREEDS IDgene:3051
Cell TypeProstate
Gene Symbol (human)FOXA1
Gene Symbol (mouse)Foxa1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1194635, GSM1194636, GSM1194637
Perturbed SamplesGSM1194634, GSM1194638, GSM1194639
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49153
Gene Expression Omnibus
FOXA1 overexpression effect on prostate cancer cell line
35
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