Small molecules which reverse REST Drug inhibition (X5050)
Canned Analysis
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General Information
AccessionDCA00020936
TitleSmall molecules which reverse REST Drug inhibition (X5050)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by REST Drug inhibition (X5050) in the NSCs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f967e467bea600fb9e98
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1710
Cell TypeNSCs
Gene Symbol (human)REST
Gene Symbol (mouse)Rest
Organismhuman
Perturbation TypeDrug inhibition (X5050)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM999257, GSM999258, GSM999259
Perturbed SamplesGSM999260, GSM999261, GSM999262
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40695
Gene Expression Omnibus
Expression data from NSCs treated with REST inhibitor X5050
7
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