Small molecules which mimic POU1F1 Snell mutant PIT1-dw
Canned Analysis
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General Information
AccessionDCA00020973
TitleSmall molecules which mimic POU1F1 Snell mutant PIT1-dw
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by POU1F1 Snell mutant PIT1-dw in the liver (22 month) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d209aee467bea600fba5bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1729
Cell Typeliver (22 month)
Gene Symbol (human)POU1F1
Gene Symbol (mouse)Pou1f1
Organismmouse
Perturbation TypeSnell mutant PIT1-dw
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM69707, GSM69708, GSM69709
Perturbed SamplesGSM69710, GSM69711, GSM69712
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3129
Gene Expression Omnibus
Age effect on livers of long-lived Snell dwarf mutants
14
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