Small molecules which mimic IKZF1 IkL/L mutation
Canned Analysis
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General Information
AccessionDCA00020977
TitleSmall molecules which mimic IKZF1 IkL/L mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by IKZF1 IkL/L mutation in the thymocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20540e467bea600fba3c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1730
Cell Typethymocytes
Gene Symbol (human)IKZF1
Gene Symbol (mouse)Ikzf1
Organismmouse
Perturbation TypeIkL/L mutation
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM47606, GSM47607
Perturbed SamplesGSM47608, GSM47609
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2501
Gene Expression Omnibus
Ikaros mutant thymic tumors
28
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