Small molecules which reverse IKZF1 IkL/L Mutation
Canned Analysis
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General Information
AccessionDCA00020980
TitleSmall molecules which reverse IKZF1 IkL/L Mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IKZF1 IkL/L Mutation in the Analysis of thymic tumors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2066ae467bea600fba44e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:2259
Cell TypeAnalysis of thymic tumors
Gene Symbol (human)IKZF1
Gene Symbol (mouse)Ikzf1
Organismhuman
Perturbation TypeIkL/L Mutation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM47606, GSM47607
Perturbed SamplesGSM47600, GSM47601, GSM47602, GSM47603, GSM47604, GSM47605, GSM47608, GSM47609
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2501
Gene Expression Omnibus
Ikaros mutant thymic tumors
28
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