Small molecules which mimic IGHMBP2 mutation Ighmbp2nmd-2J (homozygous)
Canned Analysis
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General Information
AccessionDCA00020981
TitleSmall molecules which mimic IGHMBP2 mutation Ighmbp2nmd-2J (homozygous)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by IGHMBP2 mutation Ighmbp2nmd-2J (homozygous) in the lumbar spinal cord cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20537e467bea600fba3c4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1731
Cell Typelumbar spinal cord
Gene Symbol (human)IGHMBP2
Gene Symbol (mouse)Ighmbp2
Organismmouse
Perturbation Typemutation Ighmbp2nmd-2J (homozygous)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM67523, GSM67524, GSM67525
Perturbed SamplesGSM67526, GSM67529, GSM67530
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3075
Gene Expression Omnibus
Neuromuscular degeneration mutant spinal cord response to neural stem cell transplantation
12
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