Small molecules which mimic GFI1 KO
Canned Analysis
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General Information
AccessionDCA00021007
TitleSmall molecules which mimic GFI1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GFI1 KO in the HSC cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d221dbe467bea600fbb02c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:174
Cell TypeHSC
Gene Symbol (human)GFI1
Gene Symbol (mouse)Gfi1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM508531, GSM508532, GSM508533
Perturbed SamplesGSM508528, GSM508529, GSM508530
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE20282
Gene Expression Omnibus
Growth factor independence 1 knockout effect on LSK hematopoietic stem bone marrow cells
7
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