Small molecules which mimic EP300 KD
Canned Analysis
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General Information
AccessionDCA00021017
TitleSmall molecules which mimic EP300 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by EP300 KD in the hippocampus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2145de467bea600fbaa70
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1746
Cell Typehippocampus
Gene Symbol (human)EP300
Gene Symbol (mouse)Ep300
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM458550, GSM458551, GSM458552
Perturbed SamplesGSM458547, GSM458548, GSM458549
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE18383
Gene Expression Omnibus
p300 genetic reduction model of Rubinstein-Taybi syndrome: hippocampus
7
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