Small molecules which reverse FH mutation (unspecified)
Canned Analysis
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General Information
AccessionDCA00021020
TitleSmall molecules which reverse FH mutation (unspecified)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FH mutation (unspecified) in the Uterine fibroid tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21469e467bea600fbaa76
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1747
Cell TypeUterine fibroid tissue
Gene Symbol (human)FH
Gene Symbol (mouse)Fh1
Organismhuman
Perturbation Typemutation (unspecified)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM38674, GSM38675, GSM38676, GSM38677, GSM38678, GSM38679, GSM38680, GSM38681, GSM38682, GSM38683, GSM38684, GSM38685, GSM38686, GSM38687, GSM38688
Perturbed SamplesGSM38689, GSM38690, GSM38691, GSM38692, GSM38693, GSM38694, GSM38695
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2152
Gene Expression Omnibus
Uterine fibroids with fumarate hydratase mutations
7
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