Small molecules which reverse NCSTN KD
Canned Analysis
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General Information
AccessionDCA00021022
TitleSmall molecules which reverse NCSTN KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NCSTN KD in the HEK001 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d214b4e467bea600fbaa96
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1748
Cell TypeHEK001
Gene Symbol (human)NCSTN
Gene Symbol (mouse)Ncstn
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1398420, GSM1398421, GSM1398422
Perturbed SamplesGSM1398417, GSM1398418, GSM1398419
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE57949
Gene Expression Omnibus
Effects of nicastrin (NCSTN) siRNA knockdown in HEK293 and HEK001 cells.
14
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