Small molecules which mimic NCSTN KD
Canned Analysis
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General Information
AccessionDCA00021023
TitleSmall molecules which mimic NCSTN KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NCSTN KD in the HEK293 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d214bae467bea600fbaa98
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1749
Cell TypeHEK293
Gene Symbol (human)NCSTN
Gene Symbol (mouse)Ncstn
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1398426, GSM1398427, GSM1398428
Perturbed SamplesGSM1398423, GSM1398424, GSM1398425
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE57949
Gene Expression Omnibus
Effects of nicastrin (NCSTN) siRNA knockdown in HEK293 and HEK001 cells.
14
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