Small molecules which mimic HNF1B Over-expression - (HNF1beta A263insGG mutant)
Canned Analysis
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General Information
AccessionDCA00021027
TitleSmall molecules which mimic HNF1B Over-expression - (HNF1beta A263insGG mutant)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HNF1B Over-expression - (HNF1beta A263insGG mutant) in the HEK293 embryonic kidney cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ecbe467bea600fba804
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1750
Cell TypeHEK293 embryonic kidney cells
Gene Symbol (human)HNF1B
Gene Symbol (mouse)Hnf1b
Organismhuman
Perturbation TypeOver-expression - (HNF1beta A263insGG mutant)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM74421, GSM74423
Perturbed SamplesGSM74420, GSM74422
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3308
Gene Expression Omnibus
Hepatocyte nuclear factor 1beta mutant overexpression effect on embryonic kidney cells
21
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