Small molecules which reverse IFNB1 Induction
Canned Analysis
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General Information
AccessionDCA00021034
TitleSmall molecules which reverse IFNB1 Induction
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IFNB1 Induction in the Wildtype embryo fibroblasts (MEFs) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ee1e467bea600fba80e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1752
Cell TypeWildtype embryo fibroblasts (MEFs)
Gene Symbol (human)IFNB1
Gene Symbol (mouse)Ifnb1
Organismmouse
Perturbation TypeInduction
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM76653, GSM76654, GSM76655
Perturbed SamplesGSM76656, GSM76657, GSM76658
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3400
Gene Expression Omnibus
Fibroblasts induced to an antiviral state by interferon-beta
7
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