Small molecules which reverse TRAC Stimulation ( anti-α-chain (aVα2))
Canned Analysis
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General Information
AccessionDCA00021040
TitleSmall molecules which reverse TRAC Stimulation ( anti-α-chain (aVα2))
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TRAC Stimulation ( anti-α-chain (aVα2)) in the Thymocytes (CD4+CD8+ double positive) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ea9e467bea600fba7f6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1755
Cell TypeThymocytes (CD4+CD8+ double positive)
Gene Symbol (human)TRAC
Organismmouse
Perturbation TypeStimulation ( anti-α-chain (aVα2))
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM24449, GSM24452
Perturbed SamplesGSM24450, GSM24453
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1448
Gene Expression Omnibus
Thymocyte response to anti-T cell receptor antibody stimulation
14
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