Small molecules which reverse RING1 KO
Canned Analysis
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General Information
AccessionDCA00021056
TitleSmall molecules which reverse RING1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RING1 KO in the GV oocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2214fe467bea600fbafee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1763
Cell TypeGV oocyte
Gene Symbol (human)RING1
Gene Symbol (mouse)Ring1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM568469, GSM568470, GSM568471
Perturbed SamplesGSM568472, GSM568473, GSM568474
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23033
Gene Expression Omnibus
Polycomb function during oogenesis is required for mouse early embryonic development (germinal vesicle oocytes)
14
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