Small molecules which reverse RNF2 KO
Canned Analysis
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General Information
AccessionDCA00021058
TitleSmall molecules which reverse RNF2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RNF2 KO in the GV oocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2212be467bea600fbafde
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1765
Cell TypeGV oocyte
Gene Symbol (human)RNF2
Gene Symbol (mouse)Rnf2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM568469, GSM568470, GSM568471
Perturbed SamplesGSM568475, GSM568476, GSM568477
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23033
Gene Expression Omnibus
Polycomb function during oogenesis is required for mouse early embryonic development (germinal vesicle oocytes)
14
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