Small molecules which reverse ZFX KO
Canned Analysis
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General Information
AccessionDCA00021066
TitleSmall molecules which reverse ZFX KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ZFX KO in the hematopoietic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d221b0e467bea600fbb01a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:178
Cell Typehematopoietic stem cells
Gene Symbol (human)ZFX
Gene Symbol (mouse)Zfx
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM169465, GSM169466
Perturbed SamplesGSM169463, GSM169464
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7069
Gene Expression Omnibus
Transcription factor Zfx deficiency effect on embryonic and hematopoietic stem cells
14
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