Small molecules which reverse CYR61 doxcicline mediated induction
Canned Analysis
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General Information
AccessionDCA00021068
TitleSmall molecules which reverse CYR61 doxcicline mediated induction
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CYR61 doxcicline mediated induction in the LN229 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21ae3e467bea600fbad4e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorstevann
CREEDS IDgene:1771
Cell TypeLN229
Gene Symbol (human)CYR61
Gene Symbol (mouse)Cyr61
Organismhuman
Perturbation Typedoxcicline mediated induction
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM726290, GSM726291, GSM726292
Perturbed SamplesGSM726287, GSM726288, GSM726289
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE29384
Gene Expression Omnibus
Extracellular matrix protein cysteine rich 61 (CCN1) effect on LN229 glioma cells
7
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