Small molecules which reverse RP1 KO
Canned Analysis
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General Information
AccessionDCA00021072
TitleSmall molecules which reverse RP1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RP1 KO in the Retina - 10 Days cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b08e467bea600fbad5e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1774
Cell TypeRetina - 10 Days
Gene Symbol (human)RP1
Gene Symbol (mouse)Rp1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM3187, GSM3214, GSM3215
Perturbed SamplesGSM3228, GSM3229, GSM3230
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE128
Gene Expression Omnibus
Retinitis pigmentosa 1 gene knockout effect on retinas: time course
47
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