Small molecules which mimic RP1 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021075
TitleSmall molecules which mimic RP1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RP1 KO in the Retina - 18 Days cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21aeae467bea600fbad50
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1777
Cell TypeRetina - 18 Days
Gene Symbol (human)RP1
Gene Symbol (mouse)Rp1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM3219, GSM3220, GSM3221
Perturbed SamplesGSM3234, GSM3235, GSM3236
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE128
Gene Expression Omnibus
Retinitis pigmentosa 1 gene knockout effect on retinas: time course
47
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.