Small molecules which mimic ATM knockdown
Canned Analysis
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General Information
AccessionDCA00021093
TitleSmall molecules which mimic ATM knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ATM knockdown in the HEK293 exposed to neocarzinostatin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f5b3e467bea600fb9d32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1865
Cell TypeHEK293 exposed to neocarzinostatin
Gene Symbol (human)ATM
Gene Symbol (mouse)Atm
Organismhuman
Perturbation Typeknockdown
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM28633, GSM28634, GSM28635, GSM28636, GSM28637, GSM28638
Perturbed SamplesGSM28639, GSM28640, GSM28641, GSM28642, GSM28643, GSM28644
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1676
Gene Expression Omnibus
siRNA knockdown and transcriptional response to DNA damage
35
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