Small molecules which mimic STAT3 KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021105
TitleSmall molecules which mimic STAT3 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by STAT3 KD in the Esophagus cell line OE33 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2266fe467bea600fbb22c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1790
Cell TypeEsophagus cell line OE33
Gene Symbol (human)STAT3
Gene Symbol (mouse)Stat3
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1156629, GSM1156630, GSM1156631
Perturbed SamplesGSM1156632, GSM1156633, GSM1156634
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47763
Gene Expression Omnibus
STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barretts adenocarcinomas
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.