Small molecules which reverse CFTR Deficiency
Canned Analysis
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General Information
AccessionDCA00021118
TitleSmall molecules which reverse CFTR Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CFTR Deficiency in the Lungs of C57BL/6J (B6) - Female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2268ce467bea600fbb23a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1795
Cell TypeLungs of C57BL/6J (B6) - Female
Gene Symbol (human)CFTR
Gene Symbol (mouse)Cftr
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM69246, GSM69248, GSM69249
Perturbed SamplesGSM69252, GSM69253, GSM69254
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3100
Gene Expression Omnibus
Cystic fibrosis transmembrane conductance regulator deficiency in different genetic backgrounds
50
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