Small molecules which mimic CFTR Deficiency
Canned Analysis
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General Information
AccessionDCA00021119
TitleSmall molecules which mimic CFTR Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CFTR Deficiency in the Lungs of BALB/c (BALB) - Female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d226b6e467bea600fbb24c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1798
Cell TypeLungs of BALB/c (BALB) - Female
Gene Symbol (human)CFTR
Gene Symbol (mouse)Cftr
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM69263, GSM69264, GSM69265
Perturbed SamplesGSM69260, GSM69261, GSM69262
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3100
Gene Expression Omnibus
Cystic fibrosis transmembrane conductance regulator deficiency in different genetic backgrounds
50
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