Small molecules which reverse PARK2 KD
Canned Analysis
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General Information
AccessionDCA00021126
TitleSmall molecules which reverse PARK2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PARK2 KD in the SF539 GBM cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d226b0e467bea600fbb24a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1799
Cell TypeSF539 GBM cell line
Gene Symbol (human)PARK2
Gene Symbol (mouse)Park2
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1231292, GSM1231293
Perturbed SamplesGSM1231294, GSM1231295
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50864
Gene Expression Omnibus
E3 ubiquitin ligase PARK2 depletion effect on SF539 glioma cell line
28
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