Small molecules which mimic AGO1 KD
Canned Analysis
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General Information
AccessionDCA00021131
TitleSmall molecules which mimic AGO1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by AGO1 KD in the PC-3 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d201f6e467bea600fba258
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1802
Cell TypePC-3 cells
Gene Symbol (human)AGO1
Gene Symbol (mouse)Ago1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1045748, GSM1045749
Perturbed SamplesGSM1045750, GSM1045751
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE42600
Gene Expression Omnibus
Gene expression profiling in cells with Ago1 knockdown (Affymetrix)
7
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