Small molecules which reverse TCOF1 OE
Canned Analysis
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General Information
AccessionDCA00021146
TitleSmall molecules which reverse TCOF1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TCOF1 OE in the neuroblastoma N1E-115 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f798e467bea600fb9e08
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:181
Cell Typeneuroblastoma N1E-115 cells
Gene Symbol (human)TCOF1
Gene Symbol (mouse)Tcof1
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM34977, GSM34978, GSM34979
Perturbed SamplesGSM34968, GSM34969, GSM34970
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1956
Gene Expression Omnibus
Treacher Collins' syndrome Tcof1 gene overexpression and knockdown effect on neuroblastoma cells
14
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