Small molecules which reverse TGFB1I1 KD
Canned Analysis
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General Information
AccessionDCA00021186
TitleSmall molecules which reverse TGFB1I1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TGFB1I1 KD in the Immortalized AR positive myofibroblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20adde467bea600fba642
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1823
Cell TypeImmortalized AR positive myofibroblast
Gene Symbol (human)TGFB1I1
Gene Symbol (mouse)Tgfb1i1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1146791, GSM1146792, GSM1146793
Perturbed SamplesGSM1146797, GSM1146798, GSM1146799
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47203
Gene Expression Omnibus
Genome-wide expression profiling of Hic-5 knockdown in PshTert-AR human myofibroblasts
14
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