Small molecules which reverse KDM5A KD
Canned Analysis
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General Information
AccessionDCA00021190
TitleSmall molecules which reverse KDM5A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KDM5A KD in the cell line: ONS76 cell type: medulloblastoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20b3fe467bea600fba66e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1828
Cell Typecell line: ONS76 cell type: medulloblastoma
Gene Symbol (human)KDM5A
Gene Symbol (mouse)Kdm5a
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1065188, GSM1065189, GSM1065190
Perturbed SamplesGSM1065185, GSM1065186, GSM1065187
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE43552
Gene Expression Omnibus
Expression profiling of human medulloblastoma cell line ONS76 upon siRNA-mediated knockdown of KDM5A/LSD1
7
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