Small molecules which mimic NFE2L2 KO
Canned Analysis
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General Information
AccessionDCA00021195
TitleSmall molecules which mimic NFE2L2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NFE2L2 KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2237ee467bea600fbb0e0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2190
Cell Typeliver
Gene Symbol (human)NFE2L2
Gene Symbol (mouse)Nfe2l2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM227407, GSM227408, GSM227409
Perturbed SamplesGSM227410, GSM227411, GSM227412
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8969
Gene Expression Omnibus
Nrf2 deficiency effect on the liver
12
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