Small molecules which reverse OGT small molecule inhibition
Canned Analysis
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General Information
AccessionDCA00021210
TitleSmall molecules which reverse OGT small molecule inhibition
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by OGT small molecule inhibition in the prostate cancer cells, 12 hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21111e467bea600fba902
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1838
Cell Typeprostate cancer cells, 12 hours
Gene Symbol (human)OGT
Gene Symbol (mouse)Ogt
Organismhuman
Perturbation Typesmall molecule inhibition
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1088015, GSM1088023, GSM1088031
Perturbed SamplesGSM1088016, GSM1088024, GSM1088032
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE44624
Gene Expression Omnibus
Glycosylation regulates the stability of c-MYC
35
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