Small molecules which mimic MYC OE
Canned Analysis
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General Information
AccessionDCA00021223
TitleSmall molecules which mimic MYC OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MYC OE in the lung adenocarcinomas alveolar epithelia cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f77ae467bea600fb9dfa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:184
Cell Typelung adenocarcinomas alveolar epithelia
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM277580, GSM277581, GSM277582, GSM277583
Perturbed SamplesGSM277576, GSM277577, GSM277578, GSM277579
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10954
Gene Expression Omnibus
c-Myc transgenic model of lung adenocarcinomas
7
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