Small molecules which reverse SMCHD1 KO
Canned Analysis
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General Information
AccessionDCA00021230
TitleSmall molecules which reverse SMCHD1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SMCHD1 KO in the pre-B cells, day E17.5, C57BL/6 Eµ-Myc cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d239c7e467bea600fbbab6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1845
Cell Typepre-B cells, day E17.5, C57BL/6 Eµ-Myc
Gene Symbol (human)SMCHD1
Gene Symbol (mouse)Smchd1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1004036, GSM1004038, GSM1004040
Perturbed SamplesGSM1004037, GSM1004039, GSM1004041
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40879
Gene Expression Omnibus
The effect on gene expression of Smchd1 deletion in pre-B cells from E17.5 E-Myc embryos
7
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