Small molecules which mimic MYC knock-in
Canned Analysis
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General Information
AccessionDCA00021233
TitleSmall molecules which mimic MYC knock-in
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MYC knock-in in the germinal center B-cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d239d7e467bea600fbbabc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1847
Cell Typegerminal center B-cells
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismmouse
Perturbation Typeknock-in
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM968811, GSM968813
Perturbed SamplesGSM968810, GSM968812
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39443
Gene Expression Omnibus
Genome wide analysis of germinal center MYC positive B-cells
7
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