Small molecules which reverse FGFR1 activemutant
Canned Analysis
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General Information
AccessionDCA00021236
TitleSmall molecules which reverse FGFR1 activemutant
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FGFR1 activemutant in the mammary gland cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f053e467bea600fb9ae0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1850
Cell Typemammary gland
Gene Symbol (human)FGFR1
Gene Symbol (mouse)Fgfr1
Organismmouse
Perturbation Typeactivemutant
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM72723, GSM72730, GSM72795, GSM72877
Perturbed SamplesGSM72724, GSM72787, GSM72794, GSM72876
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3260
Gene Expression Omnibus
Fibroblast growth factor receptor 1 activation effect on mammary glands: time course
21
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