Small molecules which mimic ERBB2 druginhibition
Canned Analysis
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General Information
AccessionDCA00021241
TitleSmall molecules which mimic ERBB2 druginhibition
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ERBB2 druginhibition in the skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f047e467bea600fb9ada
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1853
Cell Typeskin
Gene Symbol (human)ERBB2
Gene Symbol (mouse)Erbb2
Organismmouse
Perturbation Typedruginhibition
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM93177, GSM93178, GSM93179, GSM93180
Perturbed SamplesGSM93193, GSM93194, GSM93195, GSM93196
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4066
Gene Expression Omnibus
UV irradiation effect on skin inactivated for tyrosine kinase receptor ErbB2: time course
21
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