Small molecules which mimic LCK knockout
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00021253
TitleSmall molecules which mimic LCK knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LCK knockout in the Jurkat cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f5f2e467bea600fb9d4e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1868
Cell TypeJurkat
Gene Symbol (human)LCK
Gene Symbol (mouse)Lck
Organismhuman
Perturbation Typeknockout
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM89759, GSM89760, GSM89764
Perturbed SamplesGSM89761, GSM89763, GSM89773
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3922
Gene Expression Omnibus
T cell receptor-independent basal signaling in unstimulated Jurkat T cells
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.