Small molecules which mimic RET mutant
Canned Analysis
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General Information
AccessionDCA00021259
TitleSmall molecules which mimic RET mutant
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RET mutant in the thyroid cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fb46e467bea600fb9f66
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1870
Cell Typethyroid
Gene Symbol (human)RET
Gene Symbol (mouse)Ret
Organismmouse
Perturbation Typemutant
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM270854, GSM271092, GSM271093
Perturbed SamplesGSM271173, GSM271174, GSM271175
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10743
Gene Expression Omnibus
Thyroid carcinoma models
7
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