Small molecules which mimic ABL1 mutant
Canned Analysis
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General Information
AccessionDCA00021261
TitleSmall molecules which mimic ABL1 mutant
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ABL1 mutant in the cord blood CD34+ cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fb4fe467bea600fb9f6a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1871
Cell Typecord blood CD34+ cells
Gene Symbol (human)ABL1
Gene Symbol (mouse)Abl1
Organismhuman
Perturbation Typemutant
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM397303, GSM397307, GSM397311
Perturbed SamplesGSM397304, GSM397308, GSM397312
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15811
Gene Expression Omnibus
Fusion oncogenes ZMYM2/FGFR1, BCR/FGFR1 or BCR/ABL1 in cord blood CD34+ cells
21
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