Small molecules which reverse MYLK knockdown
Canned Analysis
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General Information
AccessionDCA00021280
TitleSmall molecules which reverse MYLK knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYLK knockdown in the lung following SB inflammatory injury cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22536e467bea600fbb1a2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1887
Cell Typelung following SB inflammatory injury
Gene Symbol (human)MYLK
Gene Symbol (mouse)Mylk
Organismmouse
Perturbation Typeknockdown
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM363525, GSM363526, GSM363527
Perturbed SamplesGSM363531, GSM363532, GSM363533
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE14525
Gene Expression Omnibus
Non muscle myosin light chain kinase isoform is an attractive molecular target in acute inflammatory lung injury
14
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