Small molecules which mimic STK33 knockdown
Canned Analysis
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General Information
AccessionDCA00021283
TitleSmall molecules which mimic STK33 knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by STK33 knockdown in the SKM-1 and NOMO-1 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2254ee467bea600fbb1ac
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1889
Cell TypeSKM-1 and NOMO-1
Gene Symbol (human)STK33
Gene Symbol (mouse)Stk33
Organismhuman
Perturbation Typeknockdown
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM378547, GSM378548, GSM378551, GSM378552
Perturbed SamplesGSM378545, GSM378546, GSM378549, GSM378550
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15151
Gene Expression Omnibus
Synthetic Lethal Interaction Between Oncogenic KRAS Dependency and Suppression of STK33 in Human Cancer Cells
7
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