Small molecules which reverse CDK9 knockdown
Canned Analysis
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General Information
AccessionDCA00021314
TitleSmall molecules which reverse CDK9 knockdown
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CDK9 knockdown in the U2OS cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fa7be467bea600fb9f10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1900
Cell TypeU2OS
Gene Symbol (human)CDK9
Gene Symbol (mouse)Cdk9
Organismhuman
Perturbation Typeknockdown
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM542331, GSM542332, GSM542333, GSM542334
Perturbed SamplesGSM542327, GSM542328, GSM542329, GSM542330
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21751
Gene Expression Omnibus
Gene expression following CDK9 silencing
7
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